A powerful suicide car bombing near the US embassy in Kabul has killed at least 16 people, including two American soldiers.
The blast on Friday also wounded two US soldiers and an unknown number of other people.
US military officials say the bomber set off his explosives in the Afghan capital as a US convoy passed by.
In western Afghanistan, a bomb attack wounded four Italian soldiers.
NATO defense chiefs reached a broad agreement on Friday that alliance troops in Afghanistan need reinforcements. NATO's top commander, General James Jones, said alliance forces still need more than two thousand additional soldiers and more helicopters and transport planes.
NATO forces are cracking down on Taleban hideouts in southern Afghanistan, and some 300 suspected militants were killed over the past week.